Hepatology a clinical textbook 4th edition

Chủ biên: Stefan Mauss, Thomas Berg, Jürgen Rockstroh, Christoph Sarrazin, Heiner Wedemeyer

Nhà xuất bản: Flying Publisher

Năm xuất bản: 2013

Ngôn ngữ: English

It is our pleasure to present the 4th Edition of Hepatology - A Clinical Textbook, which maintains the book as an up-to-date reference for all relevant aspects of clinical hepatology. This would not have been possible without the continuous contributions of all the authors who have dutifully and elegantly revised and updated their chapters. Again, the book is available in print, but probably more important as a free download at www.hepatologytextbook.com. Feedback from our readers is always welcome. And as in editions past, if you translate it, please let us know! 

The Editors
Stefan Mauss
Thomas Berg
Jürgen Rockstroh
Christoph Sarrazin
Heiner Wedemeyer

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Hepatology A Clinical Textbook 5th edition

Chủ biên: Stefan Mauss, Thomas Berg, Jürgen Rockstroh, Christoph Sarrazin, Heiner Wedemeyer

Nhà xuất bản: Flying Publisher

Năm xuất bản: 2014

Ngôn ngữ: English

Hepatology is a rapidly evolving medical field and will continue to be very exciting over the next few decades. The situation in viral hepatitis is similar to the HIV field 10-15 years ago when it started to become better understood and treatable. Today, hepatitis B viral replication can be suppressed by potent antiviral drugs but there are risks for the emergence of resistance. Strategies to enhance the eradication rates of HBV infection still need to be developed. On the other hand, hepatitis C virus infection can be eradicated by treatment with pegylated interferon plus ribavirin. However, particularly in those infected by HCV genotype 1 the sustained virologic response rates are still suboptimal. Many new antiviral drugs, especially protease and polymerase inhibitors, are currently in preclinical and clinical development, and the first data from larger clinical trials provide some optimism that the cure rates for patients with chronic hepatitis C will be enhanced with these new agents. In other areas of hepatology, e.g., for hereditary and metabol ic liver diseases, our knowledge is rapidly increasing and new therapeutic options are on the horizon.
Are books in rapidly evolving areas such as hepatology the right medium to gather and summarize the current knowledge? Are these books not likely to be outdated the very day they are published? This is indeed a challenge that can be convincingly overcome only by rapid internet-based publishing with regular updates. Another unmatched advantage of a web-based book is the free and unrestricted access everywhere. Viral hepatitis and other liver diseases are a global burden and timely information is important for physicians, scientists, patients and health care officials all around the world.
The editors of this web-based book – Thomas Berg, Stefan Mauss, Jürgen Rockstroh, Christoph Sarrazin and Heiner Wedemeyer – are young, bright, and already internationally renowned hepatologists who have created an excellent state-of-the-art textbook on clinical hepatology. The book is well-structured and written and provides indepth information without being lengthy and redundant. I am convinced that all five will remain very active in the field and will update this book regularly as the science progresses. The book should rapidly become an international standard.

Frankfurt, 24 January 2009
​Stefan Zeuzem
 

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Hepatology a clinical textbook 2nd edition

Chủ biên: Stefan Mauss, Thomas Berg, Jürgen Rockstroh, Christoph Sarrazin, Heiner Wedemeyer

Nhà xuất bản: Flying Publisher

Năm xuất bản: 2010

Ngôn ngữ: English

Hepatology is a rapidly evolving medical field and will continue to be very exciting over the next few decades. The situation in viral hepatitis is similar to the HIV field 10-15 years ago when it started to become better understood and treatable. Today, hepatitis B viral replication can be suppressed by potent antiviral drugs but there are risks for the emergence of resistance. Strategies to enhance the eradication rates of HBV infection still need to be developed. On the other hand, hepatitis C virus infection can be eradicated by treatment with pegylated interferon plus ribavirin. However, particularly in those infected by HCV genotype 1 the sustained virologic response rates are still suboptimal. Many new antiviral drugs, especially protease and polymerase inhibitors, are currently in preclinical and clinical development, and the first data from larger clinical trials provide some optimism that the cure rates for patients with chronic hepatitis C will be enhanced with these new agents. In other areas of hepatology, e.g., for hereditary and metabol ic liver diseases, our knowledge is rapidly increasing and new therapeutic options are on the horizon.
Are books in rapidly evolving areas such as hepatology the right medium to gather and summarize the current knowledge? Are these books not likely to be outdated the very day they are published? This is indeed a challenge that can be convincingly overcome only by rapid internet-based publishing with regular updates. Another unmatched advantage of a web-based book is the free and unrestricted access everywhere. Viral hepatitis and other liver diseases are a global burden and timely information is important for physicians, scientists, patients and health care officials all around the world.
The editors of this web-based book – Thomas Berg, Stefan Mauss, Jürgen Rockstroh, Christoph Sarrazin and Heiner Wedemeyer – are young, bright, and already internationally renowned hepatologists who have created an excellent state-of-the-art textbook on clinical hepatology. The book is well-structured and written and provides indepth information without being lengthy and redundant. I am convinced that all five will remain very active in the field and will update this book regularly as the science progresses. The book should rapidly become an international standard.

Frankfurt, 24 January 2009
Stefan Zeuzem
 

Xem chi tiết

Hepatology a clinical textbook

Chủ biên: Stefan Mauss, Thomas Berg, Juergen Rockstroh, Christoph Sarrazin, Heiner Wedemeyer

Nhà xuất bản: Flying Publisher

Năm xuất bản: 2009

Ngôn ngữ: English

Hepatology is a rapidly evolving medical field and will continue to be very exciting over the next few decades. The situation in viral hepatitis is similar to the HIV field 10-15 years ago when it started to become better understood and treatable. Today, hepatitis B viral replication can be suppressed by potent antiviral drugs but there are risks for the emergence of resistance. Strategies to enhance the eradication rates of HBV infection still need to be developed. On the other hand, hepatitis C virus infection can be eradicated by treatment with pegylated interferon plus ribavirin. However, particularly in those infected by HCV genotype 1 the sustained virologic response rates are still suboptimal. Many new antiviral drugs, especially protease and polymerase inhibitors, are currently in preclinical and clinical development, and the first data from larger clinical trials provide some optimism that the cure rates for patients with chronic hepatitis C will be enhanced with these new agents. In other areas of hepatology, e.g., for hereditary and metabol ic liver diseases, our knowledge is rapidly increasing and new therapeutic options are on the horizon.
Are books in rapidly evolving areas such as hepatology the right medium to gather and summarize the current knowledge? Are these books not likely to be outdated the very day they are published? This is indeed a challenge that can be convincingly overcome only by rapid internet-based publishing with regular updates. Another unmatched advantage of a web-based book is the free and unrestricted access everywhere. Viral hepatitis and other liver diseases are a global burden and timely information is important for physicians, scientists, patients and health care officials all around the world.
The editors of this web-based book – Thomas Berg, Stefan Mauss, Jürgen Rockstroh, Christoph Sarrazin and Heiner Wedemeyer – are young, bright, and already internationally renowned hepatologists who have created an excellent state-of-the-art textbook on clinical hepatology. The book is well-structured and written and provides indepth information without being lengthy and redundant. I am convinced that all five will remain very active in the field and will update this book regularly as the science progresses. The book should rapidly become an international standard.
Frankfurt, 24 January 2009

Stefan Zeuzem
 

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Bằng chứng về sự không liên quan giữa gen interferon regulatory factor (IRF) 5 và nguy cơ bị bệnh thận Iga

Năm xuất bản: 2012

Số xuất bản: 3.0

Tác giả: Vương Tuyết Mai, Stefan H Jacobson

Interferon quy định yếu tố 5 (IRF5) đã được xác định trong nhiều nghiên cứu như một gen quan trọng trong một số bệnh qua đáp ứng trung gian miễn dịch như lupus ban đỏ hệ thống, viêm khớp dạng thấp, xơ cứng bì và hội chứng Sjogren. Bệnh thận IgA được đặc trưng bởi sự lắng đọng IgA trong khu vực gian mạch cầu thận. Mục tiêu nghiên cứu nhằm kiểm tra sự liên quan giữa các điểm biến đổi của gen IRF5 và bệnh thận IgA không được xác định. Mối liên quan của các SNPs đã chọn lựa cho nghiên cứu với sự phát triển của bệnh thận IgA. Kết quả nghiên cứu cho thấy bằng chứng không liên quan giữa các điểm biến đổi của gen IRF5 với sự phát triển của bệnh thận IgA hoặc có nguy cơ tiến triển nặng trong quần thể nghiên cứu này.

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Bằng chứng về sự không liên quan giữagen Interferonregulatory factor (IRF) 5 và nguy cơ bị bệnh thận IgA

Năm xuất bản: 2012

Số xuất bản: Phụ trương Nội khoa

Tác giả: Vương Tuyết Mai , Stefan H Jacobson

Interferon quy định yếu tố 5 (IRF5) đã được xác định trong nhiều nghiên cứu như một gen quan trọng trong một số bệnh qua đáp ứng trung gian miễn dịch như lupus ban đỏ hệ thống, viêm khớp dạng thấp, xơ cứng bì và hội chứng Sjogren. Bệnh thận IgA được đặc trưng bởi sự lắng đọng IgA rong khu vực gian mạch cầu thận. Mục tiêu nghiên cứu nhằm kiểm tra sự liên quan giữa các điểm biến đổi của gen IRF5 và bệnh thận IgA không được xác định. Mối liên quan của các SNPs đã chọn lựa cho nghiên cứu với sự phát triển của bệnh thận IgA. Kết quả nghiên cứu của chúng tôi cho thấy bằng chứng của sự không liên quan giữa các điểm biến đổi của gen IRF5 với sự phát triển của bệnh thận IgA hoặc có nguy cơ tiến triển nặng bệnh trong quần thể nghiên cứu này.

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Hepatology

Chủ biên: Stefan Mauss, Thomas Berg, Juergen Rockstroh, Christoph Sarrazin, Heiner Wedemeyer

Nhà xuất bản: Flying Publisher

Năm xuất bản: 2012

Hepatology is an ever-changing field. The editors and authors of Hepatology − A Clinical
Textbook have made every effort to provide information that is accurate and complete as of the
date of publication. However, in view of the rapid changes occurring in medical science, as well
as the possibility of human error, this site may contain technical inaccuracies, typographical or
other errors. Readers are advised to check the product information currently provided by the
manufacturer of each drug to be administered to verify the recommended dose, the method and
duration of administration, and contraindications. It is the responsibility of the treating physician
who relies on experience and knowledge about the patient to determine dosages and the best
treatment for the patient. The information contained herein is provided "as is" and without
warranty of any kind. The editors and Flying Publisher & Kamps disclaim responsibility for any
errors or omissions or for results obtained from the use of information contained herein.

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Handbook of Therapeutic Antibodies, 2nd Edition

Chủ biên: Stefan Dubel

Nhà xuất bản: Wiley Blackwell

Năm xuất bản: 2014

Ngôn ngữ: English

Still the most comprehensive reference source on the development, production and therapeutic application of antibodies, this second edition is thoroughly updated and now has 30% more content.

Volume 1 covers selection and engineering strategies for new antibodies, while the second volume presents novel therapeutic concepts and antibodies in clinical study, as well as their potential. Volumes 3 and 4 feature detailed and specific information about each antibody approved for therapeutic purposes, including clinical data. This unique handbook concludes with a compendium of marketed monoclonal antibodies and an extensive index.

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