An Introduction to Medicinal Chemistry is the leading text for university courses on this subject. Renowned for being a textbook loved equally by both students and lecturers, it presents complete coverage in an accessible and engaging style.
The text begins with the essential biochemistry on which an understanding of medicinal chemistry is built, introducing the structure and function of important drug targets. It then explores how drugs interact with the body and the consequences of those reactions. There is a section on general principles and strategies involved in discovering and designing new drugs, and another on useful ‘tools of the trade’. The text ends with a contemporary look at specific topics within medicinal chemistry, for example, antiviral and anticancer agents; cholinergics and anticholinesterases; and antiulcer agents.
This document was prepared for the World Health Organization (WHO) Global Malaria Programme by Amy Barrette and Pascal Ringwald and was reviewed by Rick Fairhurst (National Institute of Allergy and Infectious Diseases) Arjen Dondorp (Mahidol–Oxford Tropical Medicine Research Unit); Patrick ; Kachur, John MacArthur, Laurence Slutsker (Malaria Branch, Centers for Disease Control and Prevention); Christopher Plowe (University of Maryland); Christopher Dye, Kamini Mendis, Robert Newman, Peter Olumese, Jackson Sillah and Mariam Warsame (WHO). The Global Malaria Programme wishes to thank the ministries of health, nongovernmental organizations, pharmaceutical companies, public private partnerships, research institutes, subregional networks and WHO regional offices that kindly shared their data. Financial support for the preparation of this document and the WHO global database on antimalarial drug efficacy was provided by the Bill & Melinda Gates Foundation and the United States Agency for International Development
This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts.
Fully updated and revised for its second edition, the Oxford Handbook of Clinical Examination and Practical Skills is the only truly comprehensive pocket guide to all aspects of history taking, physical examination, practical procedures, data interpretation, and communication skills. Packed with expert knowledge and practical guidance it gives realistic advice on coping with common situations.
Now revised for its third edition, the Oxford Handbook of Clinical Diagnosis provides a concise and practical summary of the reasoning processes behind clear and confident diagnosis. The handbook is set out systematically with symptoms and signs through each specialty, and includes a detailed description of the basis of logical evidence-based differential diagnosis.
Now in its ninth edition, the Oxford Handbook of Clinical Medicine continues to be the definitive pocket-friendly guide to medicine. The culmination over 25 years of experience at the bedside and in the community, this handbook is packed with practical advice, wit, and wisdom.
The Oxford Handbook of Clinical Medicine presents clinical information in a clear way that makes it easy to revise, remember, and implement on the ward. It gives reliable advice on what to do, when to do it, and how to do it, with clinical photographs and diagrams that bring theory to life. Uniquely for a medical text, this book weaves history, literature, art, and philosophy into its survey of medicine, casting new light on the specialties and encouraging the reader to see beyond the practical aspects of medicine and adopt a patient-centred approach to care.
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